Life Science and Medical
When a sample can "run away" from laser light we internally call it “Biophotonics”.
Fun aside. Laser light has made significant contributions in understanding the Science of Life in the last decades. It als has had important roles in diagnosis, real-time monitoring, guiding therapy, and enabling new therapeutic strategies.
Illuminating the functionality of life with the precision of light
Light has transformed the way we see life itself. In modern biomedical research and clinical diagnostics, lasers are at the heart of innovation — driving breakthroughs from fundamental cell imaging to functional understanding. At TOPTICA, we provide laser technology that empowers scientists, engineers, and clinicians to explore biological systems with unmatched imaging quality, chemical sensitivity, 3D resolution and multi-modal flexibility.
The power of lasers in life sciences
Lasers are the cornerstone of optical imaging and analysis in life sciences. Their unique combination of wavelength, brightness, tunability, and temporal control enables researchers to visualize structures and processes at the sub-cellular and even molecular level. Whether it’s revealing intricate neural networks or tracking single molecules, photonic solutions deliver the illumination that makes discovery possible.
In confocal microscopy (LSCM), tightly focused laser beams scan biological specimens point by point, generating high-contrast optical sections with exceptional spatial resolution. Our stable, low-noise laser sources with direct modulation of all wavelengths ensure optimal excitation efficiency, no optical cross-talking and minimal photobleaching — key for long-term imaging in live-cell studies.
Our femtosecond pulsed lasers deliver the high peak power and wavelength flexibility needed for deep-tissue imaging in neuroscience, where precise optical stimulation and recording reveal the secrets of brain function and connectivity. And our fiber delivery opens new opportunities in clinical microscopy or mini-2P setups.
Two-photon excitation microscopy opens a window deep into living tissue, allowing researchers to probe neuronal circuits with minimal damage. Our femtosecond pulsed lasers deliver the high peak power and wavelength flexibility needed for deep-tissue imaging in neuroscience, where precise optical stimulation and recording reveal the secrets of brain function and connectivity. And our fiber delivery opens new opportunities in clinical microscopy or mini-2P setups.
Lightsheet microscopy (SPIM) takes optical sectioning to the next level by illuminating samples with a thin sheet of light, reducing phototoxicity while achieving fast 3D imaging. With our multi-line laser platforms, researchers can simultaneously excite multiple fluorophores to capture rich volumetric data of developing embryos, organoids, and living tissues.
Pushing beyond the diffraction limit, super-resolution techniques such as STED, SIM, PALM, and STORM demand lasers with exceptional stability, pulse control, high power levels and spectral purity. Our systems provide the timing accuracy and power consistency required to achieve nanometer-scale insights into molecular architecture.
In ophthalmology, our femtosecond lasers support cutting-edge surgical systems — from corneal surgery (LASIK, SMILE) to enhanced cataract surgery, surgery and future potential like Presbyopia and glaucoma innovations — combining precision illumination with patient safety and comfort.