FemtoFiber ultra FD
Femtosecond fiber laser with fiber delivery
A game-changer for simplifying multi-photon microscopy
FemtoFiber ultra FD
Femtosecond fiber laser with fiber delivery
Completely replacing the free-space paths between a Watt-level femtosecond laser and a two-photon microscope is a game-changer for modern microscopy. Delivering femtosecond pulses directly from the laser source to the microscope via an optical fiber enables completely new microscope designs and brings laser safety and ease of use to a new level.
In the FemtoFiber ultra FD, TOPTICA combines a polarization-maintaining hollow-core fiber with TOPTICA’s proprietary COOL technology: COOLAC offers hands-off, automated fiber coupling that eliminates manual alignment at installation, optimizes fiber coupling at the touch of a button, and monitors fiber coupling efficiency completely internally without the need for external tools or equipment. This means the fiber can stay connected to the microscope or user setup at all times.
Additionally, an integrated AOM for fast power modulation, software-controlled dispersion precompensation (GDD) and TOPTICA’s unique Clean Pulse Technology complete the laser system.
Your Benefits
No mirror alignment, no power meter
Just automated fiber coupling. TOPTICA's COOL technology saves users time and effort with its automated fiber coupling (COOLAC).
Make misalignment an impossibility
A safeguard monitor regularly checks fiber coupling efficiency for best output performance.
A safeguard monitor inside the laser regularly checks fiber coupling efficiency totally internally. There is no need for external tools or equipment, such as power meters. This means the fiber can remain connected to the microscope at all times while the user can be sure of best performance each day.
Clean Pulse Technology
TOPTICA’s unique Clean Pulse Technology provides clean, pedestal-free pulses even after the fiber for best image brightness.
Fast power control
An integrated acousto-optic modulator (AOM) enables fast power-modulation and flyback blanking in synchronization with the beam scanner. This minimizes sample damage and photo-bleaching. Also, a fast electronic trigger output is available as reference for TCSPC in FLIM and gated detection.
Main fluorophores addressed
The FemtoFiber ultra FD is ideally suited for the two-photon excitation of common fluorophores like GFP, GCaMP, RFP, mCherry, tdTomato, BFP, Alexa, NADH, FAD, auto-fluorescence or SHG-imaging.
Low cost of ownership
Robust & reliable fiber laser technology significantly reduces the cost of ownership. The laser systems require no chiller and have low power consumption. In addition, the quiet & compact laser design minimizes noise-stress to the animals while at the same time saving valuable table space.
More than 20 years of experience
TOPTICA is drawing upon 20 years of experience in developing OEM-class fiber lasers. We have tailored our FemtoFiber ultra series to provide our customers with an industrial-grade light engine for high-end applications. The reliable and compact laser design provides femtosecond pulses with high average power, excellent temporal and spatial beam quality.
Options
Pulse picker
Integration of pulse-picker for adjustable repetition rate. The pulse-picker picks single pulses from the oscillator from every second pulse down to every tenth pulse only.
Custom repetition rate
Fixed custom repitition rate provides a modified oscillator with an upon ordering pre-defined repetition rate.
FiberDock collimator
FiberDock for collimation with max 3 mm beam size (1/e²)
Related Products
Downloads
Literature
Papers
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Automated femtosecond fiber delivery for multiphoton microscopy
Laura Lohr and Joseph Mastron et al. in Proc. SPIE Paper 13856-12, Multiphoton Microscopy in the Biomedical Sciences XXVI, Conference 13856 (2026) -
Femtosecond fiber delivery at 920 nm for two-photon microscopy
Konrad Birkmeier, et al., Femtosecond fiber delivery at 920 nm for two-photon microscopy, Proc. SPIE 12847, Multiphoton Microscopy in the Biomedical Sciences XXIV, 1284703 (12 March 2024)
Application Notes
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Automated Femtosecond Fiber Delivery for Multiphoton Microscopy
Webinar, Luisa Hofmann, BioPhotonics (2025)